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Risk factors for late (28+ weeks’ gestation) stillbirth in the United States, 2014–2015

PloS one, 2023-08, Vol.18 (8), p.e0289405-e0289405 [Peer Reviewed Journal]

COPYRIGHT 2023 Public Library of Science ;2023 Tanner et al. This is an open access article distributed under the terms of the Creative Commons Attribution License: http://creativecommons.org/licenses/by/4.0/ (the “License”), which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited. Notwithstanding the ProQuest Terms and Conditions, you may use this content in accordance with the terms of the License. ;2023 Tanner et al 2023 Tanner et al ;2023 Tanner et al. This is an open access article distributed under the terms of the Creative Commons Attribution License: http://creativecommons.org/licenses/by/4.0/ (the “License”), which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited. Notwithstanding the ProQuest Terms and Conditions, you may use this content in accordance with the terms of the License. ;ISSN: 1932-6203 ;EISSN: 1932-6203 ;DOI: 10.1371/journal.pone.0289405

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  • Title:
    Risk factors for late (28+ weeks’ gestation) stillbirth in the United States, 2014–2015
  • Author: Tanner, Darren ; Murthy, Sushama ; Lavista Ferres, Juan M ; Ramirez, Jan-Marino ; Mitchell, Edwin A
  • Ehrlich, Samantha Frances
  • Subjects: Births ; Body mass ; Body mass index ; Body size ; Diabetes ; Diabetes mellitus ; Diagnosis ; Dietary supplements ; Disease control ; Fetuses ; Gestation ; Gestational age ; Health aspects ; Health risks ; High income ; Hispanic Americans ; Hypertension ; Industrialized nations ; Infants ; Medicine and Health Sciences ; Obesity ; Obstetrics ; People and Places ; Population studies ; Pregnancy ; Pregnant women ; Prenatal care ; Risk factors ; Self report ; Small for gestational age ; Smoking ; Still-birth ; Stillbirth
  • Is Part Of: PloS one, 2023-08, Vol.18 (8), p.e0289405-e0289405
  • Description: Background In the United States (US) late stillbirth (at 28 weeks or more of gestation) occurs in 3/1000 births. Aim We examined risk factors for late stillbirth with the specific goal of identifying modifiable factors that contribute substantially to stillbirth burden. Setting All singleton births in the US for 2014–2015. Methods We used a retrospective population-based design to assess the effects of multiple factors on the risk of late stillbirth in the US. Data were drawn from the US Centers for Disease Control and Prevention live birth and fetal death data files. Results There were 6,732,157 live and 18,334 stillbirths available for analysis (late stillbirth rate = 2.72/1000 births). The importance of sociodemographic determinants was shown by higher risks for Black and Native Hawaiian and Other Pacific Islander mothers compared with White mothers, mothers with low educational attainment, and older mothers. Among modifiable risk factors, delayed/absent prenatal care, diabetes, hypertension, and maternal smoking were associated with increased risk, though they accounted for only 3–6% of stillbirths each. Two factors accounted for the largest proportion of late stillbirths: high maternal body mass index (BMI; 15%) and infants who were small for gestational age (38%). Participation in the supplemental nutrition for women, infants and children program was associated with a 28% reduction in overall stillbirth burden. Conclusions This study provides population-based evidence for stillbirth risk in the US. A high proportion of late stillbirths was associated with high maternal BMI and small for gestational age, whereas participation in supplemental nutrition programs was associated with a large reduction in stillbirth burden. Addressing obesity and fetal growth restriction, as well as broadening participation in nutritional supplementation programs could reduce late stillbirths.
  • Publisher: San Francisco: Public Library of Science
  • Language: English
  • Identifier: ISSN: 1932-6203
    EISSN: 1932-6203
    DOI: 10.1371/journal.pone.0289405
  • Source: PLoS (Open access)
    PubMed Central (Open access)
    Geneva Foundation Free Medical Journals at publisher websites
    AUTh Library subscriptions: ProQuest Central
    DOAJ (Directory of Open Access Journals)

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