skip to main content
Language:
Search Limited to: Search Limited to: Resource type Show Results with: Show Results with: Search type Index

Low serum vitamin D levels increase the mortality of cardiovascular disease in older adults: A dose-response meta-analysis of prospective studies

Medicine (Baltimore), 2019-08, Vol.98 (34), p.e16733-e16733 [Peer Reviewed Journal]

Copyright © 2019 the Author(s). Published by Wolters Kluwer Health, Inc. 2019 ;ISSN: 0025-7974 ;EISSN: 1536-5964 ;DOI: 10.1097/MD.0000000000016733 ;PMID: 31441845

Full text available

Citations Cited by
  • Title:
    Low serum vitamin D levels increase the mortality of cardiovascular disease in older adults: A dose-response meta-analysis of prospective studies
  • Author: Yang, Jun ; Ou-Yang, Juan ; Huang, Ji
  • Subjects: Aged ; Aged, 80 and over ; Cardiovascular Diseases - blood ; Cardiovascular Diseases - epidemiology ; Cardiovascular Diseases - mortality ; Female ; Humans ; Male ; Meta-Analysis of Observational Studies in Epidemiology ; Middle Aged ; Prospective Studies ; Risk Factors ; Vitamin D - analogs & derivatives ; Vitamin D - blood ; Vitamin D Deficiency - epidemiology
  • Is Part Of: Medicine (Baltimore), 2019-08, Vol.98 (34), p.e16733-e16733
  • Description: Lower circulating vitamin D is common in older adults and may be a potential reversible risk factor for cardiovascular disease (CVD) in older adults, however, presented controversial results.Database was searched update to February 2018. Key data were extracted from eligible studies. Dose-response meta-analysis were conducted for synthesizing data from eligible studies.A total of 13 eligible studies involving 21,079 participants were included in this meta-analysis. Person with lower 25-hydroxyvitamin D status (25 (OH)D level <50 nmol/L) appeared to have higher mortality of CVD in older adults (RR = 1.54, 95% CI 1.24-1.91). Furthermore, a significantly higher mortality of CVD in older adults was observed for the deficient (<25 nmol/L; RR = 1.47, 95% CI 1.15-1.81) and insufficient (25-50 nmol/L; RR = 1.16, 95% CI 1.04-1.27) categories of 25 (OH)D, compared to the reference category of >75 nmol/L. Additionally, decrease of 10 nmol/L 25-hydroxyvitamin D was associated with a 7% incremental in the risk of CVD mortality in older adults.Considering these promising results, circulating vitamin D is associated with CVD mortality increment in older adults.
  • Publisher: United States: Wolters Kluwer Health
  • Language: English
  • Identifier: ISSN: 0025-7974
    EISSN: 1536-5964
    DOI: 10.1097/MD.0000000000016733
    PMID: 31441845
  • Source: Journals@Ovid Open Access Journal Collection Rolling
    IngentaConnect Backfiles
    Wolters Kluwer Open Health
    MEDLINE
    PubMed Central
    DOAJ Directory of Open Access Journals
Back to results list
INSPIRE LIBRARY - TON DUC THANG UNIVERSITY (84-028) 37 755 057 Feedback
19 Nguyen Huu Tho St. Dist.7, HCM thuvien@tdtu.edu.vn

Copyright © 2017 INSPIRE LIBRARY - TON DUC THANG UNIVERSITY

Searching Remote Databases, Please Wait