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Unusual Manifestations of Acute Cytomegalovirus Infection in Solid Organ Transplant Hosts: A Report of Two Cases

Case reports in transplantation, 2017-01, Vol.2017, p.4916973-4 [Peer Reviewed Journal]

Copyright © 2017 Alfredo Mena Lora et al. ;COPYRIGHT 2017 Hindawi Limited ;Copyright © 2017 Alfredo Mena Lora et al.; This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. ;Copyright © 2017 Alfredo Mena Lora et al. 2017 ;ISSN: 2090-6943 ;EISSN: 2090-6951 ;DOI: 10.1155/2017/4916973 ;PMID: 29085699

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Title:
Unusual Manifestations of Acute Cytomegalovirus Infection in Solid Organ Transplant Hosts: A Report of Two Cases
Author: Mena Lora, Alfredo ; Khine, Justin ; Khosrodad, Nadia ; Yeldandi, Vijay
Klinger, Marian
Subjects: Archives & records ; Biopsy ; Care and treatment ; Case Report ; Case reports ; Cytomegalovirus ; Cytomegalovirus infections ; Dermatology ; Diagnosis ; Esophagus ; Family medical history ; Health aspects ; Health risk assessment ; Hypertension ; Infections ; Infectious diseases ; Kidney diseases ; Kidney transplantation ; Medicine ; Morbidity ; Mortality ; Patient outcomes ; Patients ; Transplants & implants ; Ulcers
Is Part Of: Case reports in transplantation, 2017-01, Vol.2017, p.4916973-4
Description: Cytomegalovirus (CMV) infection is a common cause of morbidity and mortality in immunocompromised hosts. Tissue-invasive CMV disease causing ulcerative skin disease or esophageal necrosis is rare. We herein describe two cases: a 47-year-old renal and pancreas transplant recipient who presented with skin ulcerations on his elbow and a 50-year-old renal transplant recipient who presented with acute esophageal necrosis. In both, tissue biopsy revealed CMV inclusion bodies by immunohistochemical staining of infected endothelial and mucosal cells. Ganciclovir was given to both cases and full remission occurred. Due to the varying presentations of acute CMV infection in immunosuppressed hosts, high suspicion and early tissue biopsy are vital for proper diagnosis and treatment when any suspicious cutaneous or mucosal manifestations are present.
Publisher: United States: Hindawi
Language: English
Identifier: ISSN: 2090-6943
EISSN: 2090-6951
DOI: 10.1155/2017/4916973
PMID: 29085699
Source: GFMER Free Medical Journals
NCBI PubMed Central（免费）
ProQuest Central
DOAJ Directory of Open Access Journals

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Unusual Manifestations of Acute Cytomegalovirus Infection in Solid Organ Transplant Hosts: A Report of Two Cases

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