Language:

Achievement of therapeutic target in subjects on statin treatment in clinical practice. Results of the STAR (Statins Target Assessment in Real practice) study

Monaldi archives for chest disease, 2011-12, Vol.76 (4), p.160-167 [Peer Reviewed Journal]

ISSN: 1122-0643 ;PMID: 22567731

Full text available

Citations Cited by

Actions
1. Add to My Research
2. Remove from My Research
3. E-mail
4. Print
5. Permalink
6. Citation
7. EasyBib
8. EndNote
9. RefWorks
10. Delicious
11. Export RIS
12. Export BibTeX

Title:
Achievement of therapeutic target in subjects on statin treatment in clinical practice. Results of the STAR (Statins Target Assessment in Real practice) study
Author: Degli Esposti, Luca ; Sangiorgi, Diego ; Arca, Marcello ; Vigna, Giovanni B ; Budal, Stefano ; Degli Esposti, Ezio
Subjects: Aged ; Algorithms ; Azetidines - therapeutic use ; Biomarkers - blood ; Cardiovascular Diseases - blood ; Cardiovascular Diseases - complications ; Cardiovascular Diseases - drug therapy ; Cerebrovascular Disorders - blood ; Cerebrovascular Disorders - complications ; Cerebrovascular Disorders - drug therapy ; Cholesterol, LDL - blood ; Cholesterol, LDL - drug effects ; Cohort Studies ; Diabetes Complications - drug therapy ; Diabetes Mellitus - drug therapy ; Ezetimibe ; Female ; Fluorobenzenes - therapeutic use ; Follow-Up Studies ; Humans ; Hydroxymethylglutaryl-CoA Reductase Inhibitors - therapeutic use ; Hypercholesterolemia - blood ; Hypercholesterolemia - drug therapy ; Hypercholesterolemia - etiology ; Italy ; Lovastatin - therapeutic use ; Male ; Medication Adherence ; Middle Aged ; Pravastatin - therapeutic use ; Pyrimidines - therapeutic use ; Retrospective Studies ; Risk Assessment ; Risk Factors ; Rosuvastatin Calcium ; Simvastatin - therapeutic use ; Sulfonamides - therapeutic use ; Treatment Outcome
Is Part Of: Monaldi archives for chest disease, 2011-12, Vol.76 (4), p.160-167
Description: The primary aim of the STAR Study (Statins Target Assessment in Real practice) was to determine the LDL-cholesterol reduction and to analyse patient's and therapeutic factors associated to LDL-cholesterol target attainment in newly treated subjects with statins in an unselected population in clinical practice setting. Administrative databases (including pharmaceutical prescriptions and hospital admissions) and laboratory test databases (including LDL-cholesterol values) of five local health units, distributed in Emilia Romagna, Toscana and Umbria, were linked. A retrospective cohort study was conducted and all subjects aged > or =18 years with a first prescription for statins (newly treated subjects) between January 1st, 2007 and June 30th, 2008 were included. All statin prescriptions over a 12 months follow-up period were considered and used to calculate adherence to treatment. Baseline and follow-up LDL-cholesterol, respectively, were defined according to the nearest determination to the first prescription for statins and to the end of the follow-up period. A total of 3.232 subjects was included, 1.516 males (47%) and 1.716 females (53%), with an average age equal to 65.9 +/- 11.3 years. Among included subjects, 22.,6% had a gap to LDL-cholesterol target <10%, 30.0% between 10 and 29%, 20.7% between 30 and 49%, and 26.7% . or =50%. Among those with a gap to target > or =50%, 30-49%, and 10-29%, respectively, LDL-cholesterol target was attained by 7.1%, 41.8%, and 62.% of subjects. LDL-cholesterol target attainment was associated to gap to target, adherence with treatment, and type of statin.
Publisher: Italy
Language: Italian
Identifier: ISSN: 1122-0643
PMID: 22567731
Source: MEDLINE
DOAJ Directory of Open Access Journals

Back to results list


INSPIRE LIBRARY - TON DUC THANG UNIVERSITY	(84-028) 37 755 057	Feedback
19 Nguyen Huu Tho St. Dist.7, HCM	thuvien@tdtu.edu.vn	Feedback

Achievement of therapeutic target in subjects on statin treatment in clinical practice. Results of the STAR (Statins Target Assessment in Real practice) study

ISSN: 1122-0643 ;PMID: 22567731

Searching Remote Databases, Please Wait