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Management of diabetic macular edema in Japan: a review and expert opinion

Japanese journal of ophthalmology, 2018-01, Vol.62 (1), p.1-23 [Peer Reviewed Journal]

Japanese Ophthalmological Society 2017 ;Japanese Journal of Ophthalmology is a copyright of Springer, (2017). All Rights Reserved. ;ISSN: 0021-5155 ;EISSN: 1613-2246 ;DOI: 10.1007/s10384-017-0537-6 ;PMID: 29210010

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Title:
Management of diabetic macular edema in Japan: a review and expert opinion
Author: Terasaki, Hiroko ; Ogura, Yuichiro ; Kitano, Shigehiko ; Sakamoto, Taiji ; Murata, Toshinori ; Hirakata, Akito ; Ishibashi, Tatsuro
Subjects: Acuity ; Adults ; Angiogenesis Inhibitors - therapeutic use ; Combined Modality Therapy ; Diabetes ; Diabetes mellitus ; Diabetic retinopathy ; Diabetic Retinopathy - diagnosis ; Diabetic Retinopathy - therapy ; Disabled people ; Disease control ; Edema ; Epidemiology ; Expert Testimony ; Glucocorticoids - therapeutic use ; Health care ; Humans ; Laser Coagulation ; Macular Edema - diagnosis ; Macular Edema - therapy ; Medicine ; Medicine & Public Health ; Microvasculature ; Ophthalmology ; Retinopathy ; Review ; Therapy ; Vascular endothelial growth factor ; Vascular Endothelial Growth Factor A - antagonists & inhibitors ; Visual acuity ; Vitrectomy
Is Part Of: Japanese journal of ophthalmology, 2018-01, Vol.62 (1), p.1-23
Description: Diabetic retinopathy is a frequent cause of visual impairment in working-age adults (≥ 30 years) and in Japan is most commonly observed in those aged 50–69 years. Diabetic macular edema (DME) is one of the main causes of vision disturbance in diabetic retinopathy, which is a clinically significant microvascular complication of diabetes. Anti-vascular endothelial growth factor (VEGF) therapy is becoming the mainstay of treatment for DME. However, to achieve sustained long-term improvement in visual acuity, conventional laser photocoagulation, vitrectomy and steroid therapy are also expected to play a role in the treatment of DME. This review summarizes the epidemiology and pathology of diabetic retinopathy and DME, evaluates the findings regarding the diagnosis and treatment of DME, and underscores the importance of systemic management of the disease in the context of the current health care situation in Japan. Finally, the unmet needs of patients with DME and prospects for research are discussed. The weight of evidence suggests that it is important to establish a multipronged treatment strategy centered on anti-VEGF therapy.
Publisher: Tokyo: Springer Japan
Language: English
Identifier: ISSN: 0021-5155
EISSN: 1613-2246
DOI: 10.1007/s10384-017-0537-6
PMID: 29210010
Source: AUTh Library subscriptions: ProQuest Central
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Management of diabetic macular edema in Japan: a review and expert opinion

Japanese Ophthalmological Society 2017 ;Japanese Journal of Ophthalmology is a copyright of Springer, (2017). All Rights Reserved. ;ISSN: 0021-5155 ;EISSN: 1613-2246 ;DOI: 10.1007/s10384-017-0537-6 ;PMID: 29210010

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