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PO229 An atypical case of posterior reversible encephalopathy syndrome

Journal of neurology, neurosurgery and psychiatry, 2017-12, Vol.88 (Suppl 1), p.A72-A72 [Peer Reviewed Journal]

2017, Published by the BMJ Publishing Group Limited. For permission to use (where not already granted under a licence) please go to http://group.bmj.com/group/rights-licensing/permissions ;Copyright: 2017 © 2017, Published by the BMJ Publishing Group Limited. For permission to use (where not already granted under a licence) please go to http://group.bmj.com/group/rights-licensing/permissions ;ISSN: 0022-3050 ;EISSN: 1468-330X ;DOI: 10.1136/jnnp-2017-ABN.250

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  • Title:
    PO229 An atypical case of posterior reversible encephalopathy syndrome
  • Author: Hosseini, Akram A ; Ali, Fizzah ; Allroggen, Holger
  • Subjects: Edema ; Hypertension
  • Is Part Of: Journal of neurology, neurosurgery and psychiatry, 2017-12, Vol.88 (Suppl 1), p.A72-A72
  • Description: IntroductionPosterior reversible encephalopathy syndrome (PRES) typically affects the posterior subcortical white matter although more anterior involvement has been described.CaseWe report the case of a 68-year-old woman with atypical PRES, who seven month previously presented with an episode of hypertension and heart failure associated with PRES. Following a full clinical recovery within a few days, she had returned to her normal independent life. Her second presentation with malignant hypertension, renal dysfunction, single seizure and fluctuating level of consciousness was rapidly followed by tetraplegia without any lower motor neuron signs. Magnetic resonance imaging of the brain within 48 hours revealed extensive vasogenic oedema in the deep white matter in both cerebral hemispheres including the brainstem and cerebellum, as well as in the frontoparietal region and temporal lobes with diffuse post-contrast enhancement. Extensive antihypertensive therapy and subsequent improvement in renal function contributed to both clinical and radiological improvement. Prolonged rehabilitation has been required to enable functional recovery.ConclusionWe report an atypical PRES presenting with tetraplegia and reversible vasogenic oedema involving all brain areas, including temporal lobes, with diffuse post-contrast enhancement.
  • Publisher: London: BMJ Publishing Group LTD
  • Language: English
  • Identifier: ISSN: 0022-3050
    EISSN: 1468-330X
    DOI: 10.1136/jnnp-2017-ABN.250
  • Source: ProQuest One Psychology
    ProQuest Central
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