Language:

Clinical Characteristics and Outcomes of Older Patients with Coronavirus Disease 2019 (COVID-19) in Wuhan, China: A Single-Centered, Retrospective Study

The Journals of Gerontology: Series A, 2020-09, Vol.75 (9), p.1788-1795 [Peer Reviewed Journal]

The Author(s) 2020. Published by Oxford University Press on behalf of The Gerontological Society of America. All rights reserved. For permissions, please e-mail: journals.permissions@oup.com. ;2020. Notwithstanding the ProQuest Terms and Conditions, you may use this content in accordance with the associated terms available at https://academic.oup.com/journals/pages/coronavirus . ;Copyright Oxford University Press Sep 2020 ;The Author(s) 2020. Published by Oxford University Press on behalf of The Gerontological Society of America. All rights reserved. For permissions, please e-mail: journals.permissions@oup.com. 2020 ;ISSN: 1079-5006 ;EISSN: 1758-535X ;DOI: 10.1093/gerona/glaa089 ;PMID: 32279081

Digital Resources/Online E-Resources

Citations Cited by

Actions
1. Add to My Research
2. Remove from My Research
3. E-mail
4. Print
5. Permalink
6. Citation
7. EasyBib
8. EndNote
9. RefWorks
10. Delicious
11. Export RIS
12. Export BibTeX

Title:
Clinical Characteristics and Outcomes of Older Patients with Coronavirus Disease 2019 (COVID-19) in Wuhan, China: A Single-Centered, Retrospective Study
Author: Chen, TieLong ; Dai, Zhe ; Mo, Pingzheng ; Li, Xinyu ; Ma, Zhiyong ; Song, Shihui ; Chen, Xiaoping ; Luo, Mingqi ; Liang, Ke ; Gao, Shicheng ; Zhang, Yongxi ; Deng, Liping ; Xiong, Yong
Newman, Anne
Subjects: Age Factors ; Aged ; Betacoronavirus - isolation & purification ; Cause of Death ; China - epidemiology ; Clinical outcomes ; Comorbidity ; Coronavirus Infections - diagnosis ; Coronavirus Infections - epidemiology ; Coronavirus Infections - mortality ; Coronaviruses ; Cough ; COVID-19 ; Death ; Female ; Fever ; Hospitalization - statistics & numerical data ; Humans ; Male ; Middle Aged ; Multiple Organ Failure - diagnosis ; Multiple Organ Failure - epidemiology ; Multiple Organ Failure - virology ; Multivariate analysis ; Older people ; Pandemics ; Patients ; Pneumonia, Viral - diagnosis ; Pneumonia, Viral - epidemiology ; Pneumonia, Viral - mortality ; Procalcitonin ; Retrospective Studies ; Risk Assessment ; SARS-CoV-2 ; Severity of Illness Index ; Symptom Assessment - methods ; Symptom Assessment - statistics & numerical data
Is Part Of: The Journals of Gerontology: Series A, 2020-09, Vol.75 (9), p.1788-1795
Description: In December 2019, the coronavirus disease 2019 (COVID-19) emerged in Wuhan city and spread rapidly throughout China and the world. In this study, we aimed to describe the clinical course and outcomes of older patients with COVID-19. This is a retrospective investigation of hospitalized older patients with confirmed COVID-19 at Zhongnan Hospital of Wuhan University from January 1, 2020, to February 10, 2020. In total, 203 patients were diagnosed with COVID-19, with a median age of 54 years (interquartile range, 41-68; range, 20-91 years). Men accounted for 108 (53.2%) of the cases, and 55 patients (27.1%) were more than 65 years of age. Among patients who were 65 years and older, the mortality rate was 34.5% (19/55), which was significantly higher than that of the younger patients at 4.7% (7/148). Common symptoms of older patients with COVID-19 included fever (94.5%; n = 52), dry cough (69.1%; n = 38), and chest distress (63.6%; n = 35). Compared with young patients, older patients had more laboratory abnormalities and comorbidities. Through a multivariate analysis of the causes of death in older patients, we found that males, comorbidities, time from disease onset to hospitalization, abnormal kidney function, and elevated procalcitonin levels were all significantly associated with death. In the recent outbreak of COVID-19, our local hospital in Wuhan found that patients aged 65 and older had greater initial comorbidities, more severe symptoms, and were more likely to experience multiorgan involvement and death, as compared to younger patients.
Publisher: United States: Oxford University Press
Language: English
Identifier: ISSN: 1079-5006
EISSN: 1758-535X
DOI: 10.1093/gerona/glaa089
PMID: 32279081
Source: Coronavirus Research Database

Back to results list


INSPIRE LIBRARY - TON DUC THANG UNIVERSITY	(84-028) 37 755 057	Feedback
19 Nguyen Huu Tho St. Dist.7, HCM	thuvien@tdtu.edu.vn	Feedback

Clinical Characteristics and Outcomes of Older Patients with Coronavirus Disease 2019 (COVID-19) in Wuhan, China: A Single-Centered, Retrospective Study

Searching Remote Databases, Please Wait