Language:

Change in vision-related quality of life and influencing factors in Asians receiving treatment for neovascular age-related macular degeneration

British journal of ophthalmology, 2018-03, Vol.102 (3), p.377-382 [Peer Reviewed Journal]

Article author(s) (or their employer(s) unless otherwise stated in the text of the article) 2018. All rights reserved. No commercial use is permitted unless otherwise expressly granted. ;Copyright: 2018 © Article author(s) (or their employer(s) unless otherwise stated in the text of the article) 2018. All rights reserved. No commercial use is permitted unless otherwise expressly granted. ;ISSN: 0007-1161 ;EISSN: 1468-2079 ;DOI: 10.1136/bjophthalmol-2017-310532 ;PMID: 28659392

Full text available

Citations Cited by

Actions
1. Add to My Research
2. Remove from My Research
3. E-mail
4. Print
5. Permalink
6. Citation
7. EasyBib
8. EndNote
9. RefWorks
10. Delicious
11. Export RIS
12. Export BibTeX

Title:
Change in vision-related quality of life and influencing factors in Asians receiving treatment for neovascular age-related macular degeneration
Author: Fenwick, Eva K ; Cheung, Gemmy Chui Ming ; Gan, Alfred TL ; Tan, Gavin ; Lee, Shu Yen ; Wong, Doric ; Yeo, Ian ; Mathur, Ranjana ; Wong, Tien Y ; Lamoureux, Ecosse L
Subjects: Age ; Aged ; Angiogenesis Inhibitors - therapeutic use ; Asian Continental Ancestry Group - psychology ; Asian people ; Clinical trials ; Comorbidity ; Female ; Growth factors ; Humans ; Intravitreal Injections ; Longitudinal Studies ; Macular degeneration ; Male ; Middle Aged ; Ophthalmology ; Patients ; Photodynamic therapy ; Population ; Prospective Studies ; Quality of life ; Quality of Life - psychology ; Questionnaires ; Reading ; Scale models ; Sickness Impact Profile ; Singapore - epidemiology ; Surveys and Questionnaires ; Tomography, Optical Coherence ; Vascular Endothelial Growth Factor A - antagonists & inhibitors ; Visual Acuity - physiology ; Visual impairment ; Wet Macular Degeneration - drug therapy ; Wet Macular Degeneration - psychology
Is Part Of: British journal of ophthalmology, 2018-03, Vol.102 (3), p.377-382
Description: AimTo assess the change in vision-related quality of life (VRQoL) after treatment for neovascular age-related macular degeneration (nAMD) and factors influencing this change in an Asian population.MethodsIn this longitudinal study, 116 patients (mean age±SD=66.5±9.9 years; 59.5% male) who underwent treatment for nAMD were recruited from a tertiary eye centre in Singapore. Best-corrected visual acuity (BCVA) and the Impact of Vision Impairment (IVI) questionnaire were evaluated at baseline and month 12. We defined three categories of BCVA change in the treated eye: BCVA gain ≥2 lines; no change in BCVA; BCVA loss ≥2 lines. The main outcome measures were the Rasch-derived IVI Reading, Mobility, and Emotional Scores. Multivariable linear regression analyses assessed the influence of sociodemographic, clinical and treatment-related factors on change in VRQoL.ResultsFollowing treatment, mean treated-eye BCVA improved by almost 2 lines (−0.22±0.40 logMAR, p<0.001) and 43% (n=50) patients reported a gain in BCVA of ≥2 lines. Mean±SD scores for Reading, Mobility and Emotional demonstrated positive changes of 0.43±1.73, 0.45±1.54 and 0.66±1.6, respectively (p<0.001 for all). In multivariable models, a ≥2 line improvement in BCVA was independently associated with a 47% (β=0.20; CI 0.01 to 0.39) increase in Reading Scores, but was not independently associated with Mobility or Emotional Scores.ConclusionNearly half of patients undergoing treatment for nAMD reported a 2-line improvement in vision which was, in turn, associated with substantial positive increases in Reading Scores. Improvements in Mobility and Emotional Scores appear to be driven by factors other than visual acuity.
Publisher: England: BMJ Publishing Group LTD
Language: English
Identifier: ISSN: 0007-1161
EISSN: 1468-2079
DOI: 10.1136/bjophthalmol-2017-310532
PMID: 28659392
Source: MEDLINE
ProQuest Central

Back to results list


INSPIRE LIBRARY - TON DUC THANG UNIVERSITY	(84-028) 37 755 057	Feedback
19 Nguyen Huu Tho St. Dist.7, HCM	thuvien@tdtu.edu.vn	Feedback

Change in vision-related quality of life and influencing factors in Asians receiving treatment for neovascular age-related macular degeneration

Searching Remote Databases, Please Wait