Language:

Between‐year variation of MHC allele frequencies in great reed warblers: selection or drift?

Journal of evolutionary biology, 2004-05, Vol.17 (3), p.485-492 [Peer Reviewed Journal]

ISSN: 1010-061X ;ISSN: 1420-9101 ;EISSN: 1420-9101 ;DOI: 10.1111/j.1420-9101.2004.00711.x ;PMID: 15149391

Full text available

Citations Cited by

Actions
1. Add to My Research
2. Remove from My Research
3. E-mail
4. Print
5. Permalink
6. Citation
7. EasyBib
8. EndNote
9. RefWorks
10. Delicious
11. Export RIS
12. Export BibTeX

Title:
Between‐year variation of MHC allele frequencies in great reed warblers: selection or drift?
Author: Westerdahl, H. ; Hansson, B. ; Bensch, S. ; Hasselquist, D.
Subjects: Acrocephalus arundinaceus ; allele frequencies ; Analysis of Variance ; Animals ; balancing selection ; Biologi ; Biological Sciences ; bird ; Gene Frequency - genetics ; Genetic Drift ; great reed warbler ; Logistic Models ; Major Histocompatibility Complex - genetics ; major histocompatibility complex class I ; Microsatellite Repeats - genetics ; Natural Sciences ; Naturvetenskap ; passerine ; pathogen resistance ; Polymorphism, Restriction Fragment Length ; Selection, Genetic ; Songbirds - genetics ; temporal variation ; Time Factors
Is Part Of: Journal of evolutionary biology, 2004-05, Vol.17 (3), p.485-492
Description: The major histocompatibility complex (MHC) genes are extremely polymorphic and this variation is assumed to be maintained by balancing selection. Cyclic interactions between pathogens and their hosts could generate such selection, and specific MHC alleles or heterozygosity at certain MHC loci have been shown to confer resistance against particular pathogens. Here we compare the temporal variation in allele frequencies of 23 MHC class I alleles with that of 23 neutral microsatellite markers in adult great reed warblers (a passerine bird) in nine successive cohorts. Overall, the MHC alleles showed a significantly higher variation in allele frequencies between cohorts than the microsatellite alleles, using a multi‐variate genetic analysis (amova). The frequency of two specific MHC alleles, A3e (P = 0.046) and B4b (P = 0.0018), varied more between cohorts than expected from random, whereas none of the microsatellite alleles showed fluctuations exceeding the expectation from stochastic variation. These results imply that the variation in MHC allele frequencies between cohorts is not a result of demographic events, but rather an effect of selection favouring different MHC alleles in different years.
Publisher: Oxford, UK: Blackwell Science Ltd
Language: English
Identifier: ISSN: 1010-061X
ISSN: 1420-9101
EISSN: 1420-9101
DOI: 10.1111/j.1420-9101.2004.00711.x
PMID: 15149391
Source: MEDLINE
Alma/SFX Local Collection
SWEPUB Freely available online

Back to results list


INSPIRE LIBRARY - TON DUC THANG UNIVERSITY	(84-028) 37 755 057	Feedback
19 Nguyen Huu Tho St. Dist.7, HCM	thuvien@tdtu.edu.vn	Feedback

Between‐year variation of MHC allele frequencies in great reed warblers: selection or drift?

ISSN: 1010-061X ;ISSN: 1420-9101 ;EISSN: 1420-9101 ;DOI: 10.1111/j.1420-9101.2004.00711.x ;PMID: 15149391

Searching Remote Databases, Please Wait