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Cardiohepatic Interactions in Heart Failure: An Overview and Clinical Implications

Journal of the American College of Cardiology, 2013-06, Vol.61 (24), p.2397-2405 [Peer Reviewed Journal]

2014 INIST-CNRS ;Copyright © 2013 American College of Cardiology Foundation. Published by Elsevier Inc. All rights reserved. ;ISSN: 0735-1097 ;EISSN: 1558-3597 ;DOI: 10.1016/j.jacc.2013.03.042 ;PMID: 23603231 ;CODEN: JACCDI

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Title:
Cardiohepatic Interactions in Heart Failure: An Overview and Clinical Implications
Author: SAMSKY, Marc D ; PATEL, Chetan B ; DEWALD, Tracy A ; SMITH, Alastair D ; FELKER, G. Michael ; ROGERS, Joseph G ; HERNANDEZ, Adrian F
Subjects: Albumins - metabolism ; Bilirubin - metabolism ; Biological and medical sciences ; Cardiology - methods ; Cardiology. Vascular system ; gamma-Glutamyltransferase - metabolism ; Heart ; Heart Failure - complications ; Heart Failure - metabolism ; Heart Failure - mortality ; Heart Failure - therapy ; Heart failure, cardiogenic pulmonary edema, cardiac enlargement ; Humans ; Liver - injuries ; Liver Diseases - complications ; Liver Function Tests ; Medical sciences ; Prognosis ; Treatment Outcome
Is Part Of: Journal of the American College of Cardiology, 2013-06, Vol.61 (24), p.2397-2405
Description: Heart failure (HF) is a major public health problem leading to frequent hospitalizations, impaired quality of life, and shortened life expectancy. Heart failure leads to a chronic inability to meet metabolic requirements of end organs or skeletal muscle. Current literature lacks comprehensive descriptions of HF effects on hepatic function. In this review paper, we summarize the literature that is available in hopes of highlighting the key differences in clinical presentation, histological findings, and biochemical profiles of patients who present with both acute and chronic liver injury secondary to HF. We further discuss the use of liver function tests as prognostic markers in patients with HF, as well as the implications of liver injury on drug metabolism in this patient population. Finally, we provide recommendations regarding the management of both types of liver injury in HF patients.
Publisher: New York, NY: Elsevier
Language: English
Identifier: ISSN: 0735-1097
EISSN: 1558-3597
DOI: 10.1016/j.jacc.2013.03.042
PMID: 23603231
CODEN: JACCDI
Source: Geneva Foundation Free Medical Journals at publisher websites
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Cardiohepatic Interactions in Heart Failure: An Overview and Clinical Implications

2014 INIST-CNRS ;Copyright © 2013 American College of Cardiology Foundation. Published by Elsevier Inc. All rights reserved. ;ISSN: 0735-1097 ;EISSN: 1558-3597 ;DOI: 10.1016/j.jacc.2013.03.042 ;PMID: 23603231 ;CODEN: JACCDI

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