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Diastolic Heart Failure — Abnormalities in Active Relaxation and Passive Stiffness of the Left Ventricle

The New England journal of medicine, 2004-05, Vol.350 (19), p.1953-1959 [Peer Reviewed Journal]

Copyright © 2004 Massachusetts Medical Society. All rights reserved. ;2004 INIST-CNRS ;Copyright 2004 Massachusetts Medical Society ;ISSN: 0028-4793 ;EISSN: 1533-4406 ;DOI: 10.1056/NEJMoa032566 ;PMID: 15128895 ;CODEN: NEJMAG

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Title:
Diastolic Heart Failure — Abnormalities in Active Relaxation and Passive Stiffness of the Left Ventricle
Author: Zile, Michael R ; Baicu, Catalin F ; Gaasch, William H
Subjects: Biological and medical sciences ; Cardiology ; Cardiology. Vascular system ; Cardiovascular disease ; Case-Control Studies ; Complications ; Development and progression ; Diastole - physiology ; Female ; General aspects ; Health aspects ; Heart ; Heart attacks ; Heart failure ; Heart Failure - diagnostic imaging ; Heart Failure - physiopathology ; Heart failure, cardiogenic pulmonary edema, cardiac enlargement ; Heart ventricle, Left ; Humans ; Male ; Medical sciences ; Middle Aged ; Mortality ; Prospective Studies ; Stroke Volume ; Ultrasonography ; Ventricular Dysfunction, Left - physiopathology ; Ventricular Pressure
Is Part Of: The New England journal of medicine, 2004-05, Vol.350 (19), p.1953-1959
Description: This hemodynamic study provides convincing evidence that heart failure in patients with a normal left ventricular ejection fraction is due to abnormal diastolic function. Convincing evidence that heart failure in patients with a normal left ventricular ejection fraction is due to abnormal diastolic function. Heart failure is a common cause of cardiovascular disease and death and may occur in the presence of either a normal or an abnormal left ventricular ejection fraction. 1 – 3 Patients with heart failure who have a normal ejection fraction differ substantially from those with heart failure and a decreased ejection fraction in several ways, including demographic characteristics, ventricular remodeling, ventricular function, the mortality rate, underlying causal mechanisms, and pathophysiological mechanisms. 4 – 14 It is widely accepted that the pathophysiology of heart failure in patients with a decreased ejection fraction involves a predominant (though not isolated) decrease in systolic function; this association . . .
Publisher: Boston, MA: Massachusetts Medical Society
Language: English
Identifier: ISSN: 0028-4793
EISSN: 1533-4406
DOI: 10.1056/NEJMoa032566
PMID: 15128895
CODEN: NEJMAG
Source: ProQuest One Psychology
MEDLINE
Alma/SFX Local Collection
ProQuest Central

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Diastolic Heart Failure — Abnormalities in Active Relaxation and Passive Stiffness of the Left Ventricle

Copyright © 2004 Massachusetts Medical Society. All rights reserved. ;2004 INIST-CNRS ;Copyright 2004 Massachusetts Medical Society ;ISSN: 0028-4793 ;EISSN: 1533-4406 ;DOI: 10.1056/NEJMoa032566 ;PMID: 15128895 ;CODEN: NEJMAG

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