Metal-based BODIPY derivatives as multimodal tools for life sciences
TON DUC THANG University
Metal-based BODIPY derivatives as multimodal tools for life sciences
Author:
Bertrand, Benoit
;
Passador, Kévin
;
Goze, Christine
;
Denat, Franck
;
Bodio, Ewen
;
Salmain, Michèle
Subjects:
Chemical Sciences
;
Coordination chemistry
;
Medicinal Chemistry
Is Part Of:
Coordination chemistry reviews, 2018-03, Vol.358, p.108-124
Description:
Nowadays, 4,4-difluoro-4-bora-3a,4a-diaza-s-indacene – better known as BODIPY – is at the forefront of fluorophores for life sciences. Indeed, its high brightness, its tunable excitation and emission wavelengths along with its high chemical and photochemical stability draw more and more the interest of researchers. In the last decade, chemists have taken advantage of the versatility of the synthesis of BODIPY to design sophisticated objects. This review focuses on the different recent studies dealing with the conception of metal-based-BODIPY derivatives for medical purposes. More precisely, emphasis is put on the use of BODIPY derivatives for the elaboration of BODIPY-based theranostics, multimodal imaging probes, and photodynamic therapy sensitizers.
Publisher:
Elsevier
Language:
English
Identifier:
ISSN: 0010-8545
EISSN: 1873-3840
DOI: 10.1016/j.ccr.2017.12.007
Source:
Hyper Article en Ligne (HAL) (Open Access)