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Conducting proportional meta-analysis in different types of systematic reviews: a guide for synthesisers of evidence

BMC medical research methodology, 2021-09, Vol.21 (1), p.1-189, Article 189 [Peer Reviewed Journal]

COPYRIGHT 2021 BioMed Central Ltd. ;2021. This work is licensed under http://creativecommons.org/licenses/by/4.0/ (the “License”). Notwithstanding the ProQuest Terms and Conditions, you may use this content in accordance with the terms of the License. ;The Author(s) 2021 ;ISSN: 1471-2288 ;EISSN: 1471-2288 ;DOI: 10.1186/s12874-021-01381-z ;PMID: 34544368

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  • Title:
    Conducting proportional meta-analysis in different types of systematic reviews: a guide for synthesisers of evidence
  • Author: Barker, Timothy Hugh ; Migliavaca, Celina Borges ; Stein, Cinara ; Colpani, Verônica ; Falavigna, Maicon ; Aromataris, Edoardo ; Munn, Zachary
  • Subjects: Estimates ; Human papillomavirus ; Investigations ; Magnetic resonance imaging ; Medical personnel ; Medical research ; Medicine, Experimental ; Meta-analysis ; Methods ; Mortality ; Proportional meta-analysis ; Research synthesis ; Systematic review ; Systematic reviews
  • Is Part Of: BMC medical research methodology, 2021-09, Vol.21 (1), p.1-189, Article 189
  • Description: Abstract Background Single group data present unique challenges for synthesises of evidence. Proportional meta-analysis is becoming an increasingly common technique employed for the synthesis of single group data. Proportional meta-analysis shares many similarities with the conduct and reporting of comparative, or pairwise, meta-analysis. While robust and comprehensive methods exist detailing how researchers can conduct a meta-analysis that compares two (or more) groups against a common intervention, there is a scarcity of methodological guidance available to assist synthesisers of evidence in the conduct, interpretation, and importance of proportional meta-analysis in systematic reviews. Main body This paper presents an overview targeted to synthesisers of evidence and systematic review authors that details the methods, importance, and interpretation of a proportional meta-analysis. We provide worked examples of how proportional meta-analyses have been conducted in research syntheses previously and consider the methods, statistical considerations, and presentation of this technique. Conclusion This overview is designed to serve as practical guidance for synthesisers of evidence in the conduct of proportional meta-analyses.
  • Publisher: London: BioMed Central Ltd
  • Language: English
  • Identifier: ISSN: 1471-2288
    EISSN: 1471-2288
    DOI: 10.1186/s12874-021-01381-z
    PMID: 34544368
  • Source: PubMed (Medline)
    SpringerOpen
    GFMER Free Medical Journals
    Coronavirus Research Database
    ROAD: Directory of Open Access Scholarly Resources
    ProQuest Central
    DOAJ Directory of Open Access Journals
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