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Effects of durotomy versus myelotomy in the repair of spinal cord injury

Neural regeneration research, 2020-10, Vol.15 (10), p.1814-1820 [Peer Reviewed Journal]

COPYRIGHT 2020 Medknow Publications and Media Pvt. Ltd. ;2020. This article is published under (http://creativecommons.org/licenses/by-nc-sa/3.0/) (the “License”). Notwithstanding the ProQuest Terms and Conditions, you may use this content in accordance with the terms of the License. ;Copyright © Wanfang Data Co. Ltd. All Rights Reserved. ;Copyright: © 2020 Neural Regeneration Research 2020 ;ISSN: 1673-5374 ;EISSN: 1876-7958 ;DOI: 10.4103/1673-5374.280304 ;PMID: 32246622

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Title:
Effects of durotomy versus myelotomy in the repair of spinal cord injury
Author: Telemacque, Dionne ; Zhu, Feng-Zhao ; Ren, Zheng-Wei ; Chen, Kai-Fang ; Drepaul, Deepak ; Yao, Sheng ; Yang, Fan ; Qu, Yan-Zheng ; Sun, Ting-Fang ; Guo, Xiao-Dong
Subjects: Care and treatment ; Complications and side effects ; decompression; durotomy; intraspinal pressure; laminectomy; myelotomy; neurological recovery; spinal cord compartment syndrome; spinal cord injury; spinal cord interstitial pressure ; Edema ; Hemorrhage ; Ischemia ; Magnetic resonance imaging ; Medical Subject Headings-MeSH ; Methods ; Neurosurgery ; Patient outcomes ; Patients ; Review ; Spinal cord injuries ; Spinal surgery ; Trauma
Is Part Of: Neural regeneration research, 2020-10, Vol.15 (10), p.1814-1820
Description: Current management for spinal cord injury aims to reduce secondary damage and recover sensation and movement. Acute spinal cord injury is often accompanied by spinal cord compartment syndrome. Decompression by durotomy and/or myelotomy attempts to relieve secondary damage by completelyrelieving the compression of the spinal cord, removing the necrotic tissue, decreasing edema, reducing hemorrhage, and improving blood circulation in the spinal cord. However, it is controversial whether durotomy and/or myelotomy after spinal cord injury are beneficial to neurological recovery. This review compares the clinical effects of durotomy with those of myelotomy in the treatment of spinal cord injury. We found that durotomy has been performed more than myelotomy in the clinic, and that durotomy may be safer and more effective than myelotomy. Durotomy performed in humans had positive effects on neurological function in 92.3% of studies in this review, while durotomy in animals had positive effects on neurological function in 83.3% of studies. Myelotomy procedures were effective in 80% of animal studies, but only one clinical study of myelotomy has reported positive results, of motor and sensory improvement, in humans. However, a number of new animal studies have reported that durotomy and myelotomy are ineffective for spinal cord injury. More clinical data, in the form of a randomized controlled study, are needed to understand the effectiveness of durotomy and myelotomy.
Publisher: India: Wolters Kluwer India Pvt. Ltd
Language: English;Chinese
Identifier: ISSN: 1673-5374
EISSN: 1876-7958
DOI: 10.4103/1673-5374.280304
PMID: 32246622
Source: ProQuest One Psychology
Open Access: PubMed Central
AUTh Library subscriptions: ProQuest Central
GFMER Free Medical Journals
DOAJ Directory of Open Access Journals

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Effects of durotomy versus myelotomy in the repair of spinal cord injury

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