skip to main content
Language:
Search Limited to: Search Limited to: Resource type Show Results with: Show Results with: Search type Index

Gait Assessment in Chronic Inflammatory Demyelinating Polyradiculoneuropathy

Acta neurologica Scandinavica, 2024, Vol.2024 [Peer Reviewed Journal]

Copyright © 2024 Arnau Llauradó et al. ;Copyright © 2024 Arnau Llauradó et al. This is an open access article distributed under the Creative Commons Attribution License (the “License”), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. Notwithstanding the ProQuest Terms and Conditions, you may use this content in accordance with the terms of the License. https://creativecommons.org/licenses/by/4.0 ;ISSN: 0001-6314 ;EISSN: 1600-0404 ;DOI: 10.1155/2024/7037704

Full text available

Citations Cited by
  • Title:
    Gait Assessment in Chronic Inflammatory Demyelinating Polyradiculoneuropathy
  • Author: Llauradó, Arnau ; Quintana, Manuel ; Gratacós-Viñola, Margarita ; Vidal-Taboada, Jose Manuel ; Restrepo-Vera, Juan Luis ; Alemañ, José ; López-Diego, Verónica ; Salvadó, Maria ; Sanchez-Tejerina, Daniel ; Sotoca, Javier ; Raguer, Núria ; Juntas-Morales, Raul
  • Colosimo, Carlo ; Carlo Colosimo
  • Subjects: Demyelination ; Gait ; Immunoglobulins ; Inflammation ; Medical research ; Muscle strength ; Patients ; Sensitivity analysis ; Statistical analysis ; Steroids
  • Is Part Of: Acta neurologica Scandinavica, 2024, Vol.2024
  • Description: Background and Aims. Gait impairment is a common manifestation of chronic inflammatory demyelinating polyradiculoneuropathy (CIDP). However, clinicians lack an effective monitoring tool, as no gait test has been validated for CIDP. The aim of this study was to determine the usefulness of three tests in monitoring the clinical course of patients with CIDP: Timed Up and Go (TUG), 10-Meter Walk Test (10MWT), and 30-Second Chair Stand (30SCS). Methods. This is a prospective, single-center observational study. We included newly diagnosed CIDP patients starting treatment or relapsed CIDP patients requiring new treatment. We monitored the clinical course using CIDP-validated clinical scales and correlated changes in clinical status with the results of the gait tests. A ROC curve was developed, and we chose the cut-off point on each scale with the best specificity and sensitivity to detect change in clinical status. Results. A total of 20 patients have been recruited. The 3 tests show a statistical correlation with objective clinical improvement. In patients who have showed clinical improvement during the follow-up examination, a mean reduction of 4.8 seconds in TUG and 2.6 in 10MWT and a gain of 3 repetitions in 30SCS have been observed. The optimal cut-off points for each test were TUG≤1 seconds, 10MWT≤1 seconds, and 30SCS≥1 repetition. The TUG test has the highest sensitivity (82.6%), and the 30SCS test has the highest specificity (100%) for detecting clinical improvement. Conclusions. The study found that the TUG and 30SCS tests could become effective tools for monitoring treatment response in CIDP patients.
  • Publisher: Copenhagen: Hindawi
  • Language: English;French;German
  • Identifier: ISSN: 0001-6314
    EISSN: 1600-0404
    DOI: 10.1155/2024/7037704
  • Source: ProQuest Central
Back to results list
INSPIRE LIBRARY - TON DUC THANG UNIVERSITY (84-028) 37 755 057 Feedback
19 Nguyen Huu Tho St. Dist.7, HCM thuvien@tdtu.edu.vn

Copyright © 2017 INSPIRE LIBRARY - TON DUC THANG UNIVERSITY

Searching Remote Databases, Please Wait