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Estimates of the global, regional, and national morbidity, mortality, and aetiologies of diarrhoea in 195 countries: a systematic analysis for the Global Burden of Disease Study 2016

The Lancet infectious diseases, 2018-11, Vol.18 (11), p.1211-1228 [Peer Reviewed Journal]

2018 The Author(s). Published by Elsevier Ltd. This is an Open Access article under the CC BY 4.0 license ;Copyright © 2018 The Author(s). Published by Elsevier Ltd. This is an Open Access article under the CC BY 4.0 license. Published by Elsevier Ltd.. All rights reserved. ;Copyright Elsevier Limited Nov 2018 ;cc by (c) Albertson et al., 2018 info:eu-repo/semantics/openAccess http://creativecommons.org/licenses/by/3.0/es/ ;2018 The Author(s). Published by Elsevier Ltd. This is an Open Access article under the CC BY 4.0 license 2018 ;ISSN: 1473-3099 ;EISSN: 1474-4457 ;DOI: 10.1016/S1473-3099(18)30362-1 ;PMID: 30243583

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Title:
Estimates of the global, regional, and national morbidity, mortality, and aetiologies of diarrhoea in 195 countries: a systematic analysis for the Global Burden of Disease Study 2016
Author: Troeger, Christopher ; Rao, Puja C ; Cao, Shujin ; Zimsen, Stephanie RM ; Albertson, Samuel B ; Stanaway, Jeffery D ; Abebe, Zegeye ; Alvis-Guzman, Nelson ; Anteneh, Zelalem Alamrew ; Antonio, Carl Abelardo T ; Aremu, Olatunde ; Asfaw, Ephrem Tsegay ; Atey, Tesfay Mehari ; Atique, Suleman ; Avokpaho, Euripide Frinel G Arthur ; Ayele, Henok Tadesse ; Barac, Aleksandra ; Barreto, Mauricio L ; Bassat, Quique ; Belay, Saba Abraham ; Bensenor, Isabela M ; Bhutta, Zulfiqar A ; Bizuneh, Hailemichael ; Castañeda-Orjuela, Carlos A ; Dadi, Abel Fekadu ; Dandona, Lalit ; Dandona, Rakhi ; Do, Huyen Phuc ; Dubey, Manisha ; Dubljanin, Eleonora ; Edessa, Dumessa ; Endries, Aman Yesuf ; Eshrati, Babak ; Farag, Tamer ; Feyissa, Garumma Tolu ; Foreman, Kyle J ; Fullman, Nancy ; Gishu, Melkamu Dedefo ; Godwin, William W ; Gugnani, Harish Chander ; Gupta, Rahul ; Hailu, Gessessew Bugssa ; Hassen, Hamid Yimam ; Hibstu, Desalegn Tsegaw ; Ilesanmi, Olayinka S ; Jonas, Jost B ; Kahsay, Amaha ; Kasaeian, Amir ; Khader, Yousef Saleh ; Khan, Ejaz Ahmad ; Kissoon, Niranjan ; Kotloff, Karen L ; Koyanagi, Ai ; Kumar, G Anil ; Magdy Abd El Razek, Hassan ; Malekzadeh, Reza ; Mehata, Suresh ; Mendoza, Walter ; Mengistu, Desalegn Tadese ; Menota, Bereket Gebremichael ; Mlashu, Fitsum Weldegebreal ; Murthy, Srinivas ; Naik, Gurudatta A ; Ningrum, Dina Nur Anggraini ; Ogbo, Felix Akpojene ; Olagunju, Andrew Toyin ; Paudel, Deepak ; Platts-Mills, James A ; Qorbani, Mostafa ; Rafay, Anwar ; Rana, Saleem M ; Ranabhat, Chhabi Lal ; Rasella, Davide ; Ray, Sarah E ; Reis, Cesar ; Renzaho, Andre MN ; Rezai, Mohammad Sadegh ; Ruhago, George Mugambage ; Safiri, Saeid ; Sanabria, Juan Ramon ; Sawhney, Monika ; Sepanlou, Sadaf G ; Shigematsu, Mika ; Sisay, Mekonnen ; Somayaji, Ranjani ; Sreeramareddy, Chandrashekhar T ; Sykes, Bryan L ; Taffere, Getachew Redae ; Tran, Bach Xuan ; Tuem, Kald Beshir ; Ukwaja, Kingsley Nnanna ; Walson, Judd L ; Weaver, Marcia R ; Workicho, Abdulhalik ; Yonemoto, Naohiro ; El Sayed Zaki, Maysaa ; Naghavi, Mohsen ; Murray, Christopher JL ; Mokdad, Ali H ; Reiner, Robert C
Subjects: Adolescent ; Adult ; Adults ; Age ; Aged ; Aged, 80 and over ; Autopsies ; Autopsy ; Bacterial Infections - epidemiology ; Bacterial Infections - etiology ; Bacterial Infections - mortality ; Bayesian analysis ; Biostatistics ; Body height ; Charities ; Child ; Child, Preschool ; Children ; Cost of Illness ; Death ; Diarrea ; Diarrhea ; Diarrhea - epidemiology ; Diarrhea - etiology ; Diarrhea - mortality ; Disease ; Disease prevention ; Epidemiologic Methods ; Fatalities ; Female ; Global Health ; Health risks ; Humans ; Incidence ; Infant ; Infant mortality ; Infant, Newborn ; Injury analysis ; Low income groups ; Male ; Middle Aged ; Morbidity ; Mortalitat infantil ; Mortality ; Pneumonia ; Prevalence ; Registration ; Regression analysis ; Risk analysis ; Risk Factors ; Rotavirus ; Sanitation ; Survival Analysis ; Topography, Medical ; Uncertainty ; Virus Diseases - epidemiology ; Virus Diseases - etiology ; Virus Diseases - mortality ; Viruses ; Weight ; Young Adult
Is Part Of: The Lancet infectious diseases, 2018-11, Vol.18 (11), p.1211-1228
Description: The Global Burden of Diseases, Injuries, and Risk Factors Study (GBD) 2016 provides an up-to-date analysis of the burden of diarrhoea in 195 countries. This study assesses cases, deaths, and aetiologies in 1990–2016 and assesses how the burden of diarrhoea has changed in people of all ages. We modelled diarrhoea mortality with a Bayesian hierarchical modelling platform that evaluates a wide range of covariates and model types on the basis of vital registration and verbal autopsy data. We modelled diarrhoea incidence with a compartmental meta-regression tool that enforces an association between incidence and prevalence, and relies on scientific literature, population representative surveys, and health-care data. Diarrhoea deaths and episodes were attributed to 13 pathogens by use of a counterfactual population attributable fraction approach. Diarrhoea risk factors are also based on counterfactual estimates of risk exposure and the association between the risk and diarrhoea. Each modelled estimate accounted for uncertainty. In 2016, diarrhoea was the eighth leading cause of death among all ages (1 655 944 deaths, 95% uncertainty interval [UI] 1 244 073–2 366 552) and the fifth leading cause of death among children younger than 5 years (446 000 deaths, 390 894–504 613). Rotavirus was the leading aetiology for diarrhoea mortality among children younger than 5 years (128 515 deaths, 105 138–155 133) and among all ages (228 047 deaths, 183 526–292 737). Childhood wasting (low weight-for-height score), unsafe water, and unsafe sanitation were the leading risk factors for diarrhoea, responsible for 80·4% (95% UI 68·2–85·0), 72·1% (34·0–91·4), and 56·4% (49·3–62·7) of diarrhoea deaths in children younger than 5 years, respectively. Prevention of wasting in 1762 children (95% UI 1521–2170) could avert one death from diarrhoea. Substantial progress has been made globally in reducing the burden of diarrhoeal diseases, driven by decreases in several primary risk factors. However, this reduction has not been equal across locations, and burden among adults older than 70 years requires attention. Bill & Melinda Gates Foundation.
Publisher: United States: Elsevier Ltd
Language: English
Identifier: ISSN: 1473-3099
EISSN: 1474-4457
DOI: 10.1016/S1473-3099(18)30362-1
PMID: 30243583
Source: Recercat
MEDLINE
ProQuest Central

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Estimates of the global, regional, and national morbidity, mortality, and aetiologies of diarrhoea in 195 countries: a systematic analysis for the Global Burden of Disease Study 2016

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