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Triglyceride-glucose index as a marker in cardiovascular diseases: landscape and limitations

Cardiovascular diabetology, 2022-05, Vol.21 (1), p.68-68, Article 68 [Peer Reviewed Journal]

2022. The Author(s). ;2022. This work is licensed under http://creativecommons.org/licenses/by/4.0/ (the “License”). Notwithstanding the ProQuest Terms and Conditions, you may use this content in accordance with the terms of the License. ;The Author(s) 2022 ;ISSN: 1475-2840 ;EISSN: 1475-2840 ;DOI: 10.1186/s12933-022-01511-x ;PMID: 35524263

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Title:
Triglyceride-glucose index as a marker in cardiovascular diseases: landscape and limitations
Author: Tao, Li-Chan ; Xu, Jia-Ni ; Wang, Ting-Ting ; Hua, Fei ; Li, Jian-Jun
Subjects: Biomarkers ; Blood Glucose ; Cardiovascular disease ; Cardiovascular diseases ; Cardiovascular Diseases - diagnosis ; Cardiovascular Diseases - epidemiology ; Coronary vessels ; Diabetes ; Disease prevention ; Fasting ; Glucose ; Heart failure ; Humans ; Hypertension ; Insulin ; Insulin Resistance ; Metabolism ; Review ; Risk Assessment ; Risk Factors ; Triglyceride-glucose index ; Triglycerides ; Vein & artery diseases
Is Part Of: Cardiovascular diabetology, 2022-05, Vol.21 (1), p.68-68, Article 68
Description: The triglyceride-glucose (TyG) index has been identified as a reliable alternative biomarker of insulin resistance (IR). Recently, a considerable number of studies have provided robust statistical evidence suggesting that the TyG index is associated with the development and prognosis of cardiovascular disease (CVD). Nevertheless, the application of the TyG index as a marker of CVD has not systemically been evaluated, and even less information exists regarding the underlying mechanisms associated with CVD. To this end, in this review, we summarize the history of the use of the TyG index as a surrogate marker for IR. We aimed to highlight the application value of the TyG index for a variety of CVD types and to explore the potential limitations of using this index as a predictor for cardiovascular events to improve its application value for CVD and provide more extensive and precise supporting evidence.
Publisher: England: BioMed Central
Language: English
Identifier: ISSN: 1475-2840
EISSN: 1475-2840
DOI: 10.1186/s12933-022-01511-x
PMID: 35524263
Source: Freely Accessible Journals
PubMed Central (Open access)
AUTh Library subscriptions: ProQuest Central
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ROAD: Directory of Open Access Scholarly Resources

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Triglyceride-glucose index as a marker in cardiovascular diseases: landscape and limitations

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