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Systemic lupus erythematosus with trisomy X: a case report and review of the literature

Journal of medical case reports, 2022-07, Vol.16 (1), p.1-281, Article 281 [Peer Reviewed Journal]

COPYRIGHT 2022 BioMed Central Ltd. ;2022. This work is licensed under http://creativecommons.org/licenses/by/4.0/ (the “License”). Notwithstanding the ProQuest Terms and Conditions, you may use this content in accordance with the terms of the License. ;The Author(s) 2022 ;ISSN: 1752-1947 ;EISSN: 1752-1947 ;DOI: 10.1186/s13256-022-03478-5 ;PMID: 35850774

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Title:
Systemic lupus erythematosus with trisomy X: a case report and review of the literature
Author: Luo, Fang ; Ye, Qiao ; Shen, Jie
Subjects: Abdomen ; Anemia ; Antibodies ; Apoptosis ; Arthritis ; Belimumab ; Blood ; Blood diseases ; Care and treatment ; Case Report ; Case reports ; Chromosomes ; Edema ; Female ; Females ; Fever ; Hospitals ; Lupus ; Pathogenesis ; Patients ; Pleural effusion ; Proteins ; Systemic lupus erythematosus ; Tomography ; Trisomy X ; Ultrasonic imaging ; Womens health ; X chromosomes
Is Part Of: Journal of medical case reports, 2022-07, Vol.16 (1), p.1-281, Article 281
Description: Background The cause of systemic lupus erythematosus is not completely clear so far, but the prevalence of systemic lupus erythematosus is significantly increased in people with additional X chromosomes. Case presentation We report a 17-year-old Chinese female patient with systemic lupus erythematosus complicated with trisomy X, accompanied by lupus nephritis, pancytopenia, hemolytic anemia, and multiserous effusion. The patient recovered well after treatment and returned regularly. We review the previously reported cases to summarize the clinical characteristics of these patients. Conclusion The additional X chromosome is related to the development of systemic lupus erythematosus. Whether it is a subtype of systemic lupus erythematosus remains to be further confirmed. Keywords: Systemic lupus erythematosus, Trisomy X, Female
Publisher: London: BioMed Central Ltd
Language: English
Identifier: ISSN: 1752-1947
EISSN: 1752-1947
DOI: 10.1186/s13256-022-03478-5
PMID: 35850774
Source: Freely Accessible Journals
Open Access: PubMed Central
SpringerOpen
ROAD: Directory of Open Access Scholarly Resources
ProQuest Central
DOAJ Directory of Open Access Journals

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Systemic lupus erythematosus with trisomy X: a case report and review of the literature

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