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Dermatomyositis Presenting with Generalized Subcutaneous Edema

Internal Medicine, 2023/08/01, Vol.62(15), pp.2273-2277 [Peer Reviewed Journal]

2023 by The Japanese Society of Internal Medicine ;Copyright Japan Science and Technology Agency 2023 ;Copyright © 2023 by The Japanese Society of Internal Medicine ;ISSN: 0918-2918 ;EISSN: 1349-7235 ;DOI: 10.2169/internalmedicine.0687-22 ;PMID: 37532515

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Title:
Dermatomyositis Presenting with Generalized Subcutaneous Edema
Author: Nishioka, Hiroaki ; Shindo, Tatsuya ; Shimizu, Hayato
Subjects: Aged, 80 and over ; Angioedema ; anti-transcriptional intermediary factor 1-γ antibody ; Case Report ; corticosteroid ; Corticosteroids ; Dermatomyositis ; Dermatomyositis - complications ; Dermatomyositis - diagnosis ; Dermatomyositis - drug therapy ; Edema ; Edema - diagnosis ; Edema - etiology ; Exanthema ; Female ; Humans ; Internal medicine ; Muscle Weakness ; Tacrolimus
Is Part Of: Internal Medicine, 2023/08/01, Vol.62(15), pp.2273-2277
Description: Generalized subcutaneous edema is rare in dermatomyositis. We herein report an 82-year-old woman with dermatomyositis who presented with generalized subcutaneous edema. Three weeks before admission, she first noticed facial edema, and the symptoms exacerbated, with limb edema occurring. On admission, muscle weakness in the limbs and skin rash were noted. Her muscle enzyme levels were elevated, and serum anti-transcriptional intermediary factor 1-γ antibody was detected. She was diagnosed with dermatomyositis and treated with corticosteroids and tacrolimus, which improved her muscle weakness, muscle enzymes, and edema. Thus, generalized subcutaneous edema can occur during dermatomyositis, with facial edema as the initial symptom.
Publisher: Japan: The Japanese Society of Internal Medicine
Language: English
Identifier: ISSN: 0918-2918
EISSN: 1349-7235
DOI: 10.2169/internalmedicine.0687-22
PMID: 37532515
Source: MEDLINE
PubMed Central
Alma/SFX Local Collection

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Dermatomyositis Presenting with Generalized Subcutaneous Edema

2023 by The Japanese Society of Internal Medicine ;Copyright Japan Science and Technology Agency 2023 ;Copyright © 2023 by The Japanese Society of Internal Medicine ;ISSN: 0918-2918 ;EISSN: 1349-7235 ;DOI: 10.2169/internalmedicine.0687-22 ;PMID: 37532515

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