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The Author(s) 2022 ;2022. The Author(s). ;The Author(s) 2022. This work is published under http://creativecommons.org/licenses/by/4.0/ (the “License”). Notwithstanding the ProQuest Terms and Conditions, you may use this content in accordance with the terms of the License. ;ISSN: 0171-5216 ;EISSN: 1432-1335 ;DOI: 10.1007/s00432-022-04319-0 ;PMID: 36036824

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