Language:

Peritumoral edema shown by MRI predicts poor clinical outcome in glioblastoma

World journal of surgical oncology, 2015-03, Vol.13 (1), p.97-97, Article 97 [Peer Reviewed Journal]

COPYRIGHT 2015 BioMed Central Ltd. ;COPYRIGHT 2015 BioMed Central Ltd. ;Wu et al.; licensee BioMed Central. 2015 ;ISSN: 1477-7819 ;EISSN: 1477-7819 ;DOI: 10.1186/s12957-015-0496-7 ;PMID: 25886608

Full text available

Citations Cited by

Actions
1. Add to My Research
2. Remove from My Research
3. E-mail
4. Print
5. Permalink
6. Citation
7. EasyBib
8. EndNote
9. RefWorks
10. Delicious
11. Export RIS
12. Export BibTeX

Title:
Peritumoral edema shown by MRI predicts poor clinical outcome in glioblastoma
Author: Wu, Chen-Xing ; Lin, Guo-Shi ; Lin, Zhi-Xiong ; Zhang, Jian-Dong ; Liu, Shui-Yuan ; Zhou, Chang-Fu
Subjects: Adult ; Aged ; Brain Edema - etiology ; Brain Edema - mortality ; Brain Edema - pathology ; Brain Neoplasms - complications ; Brain Neoplasms - mortality ; Brain Neoplasms - surgery ; Care and treatment ; Diagnosis ; Dropsy ; Edema ; Female ; Follow-Up Studies ; Glioblastoma - complications ; Glioblastoma - mortality ; Glioblastoma - surgery ; Glioblastoma multiforme ; Health aspects ; Humans ; Magnetic resonance imaging ; Magnetic Resonance Imaging - methods ; Male ; Medical records ; Middle Aged ; Neoplasm Staging ; Patient outcomes ; Prognosis ; Retrospective Studies ; Survival Rate
Is Part Of: World journal of surgical oncology, 2015-03, Vol.13 (1), p.97-97, Article 97
Description: Magnetic resonance imaging (MRI) plays an irreplaceable role in the preoperative diagnosis of glioma, and its imaging features are the base of making treatment decisions in patients with glioma, but it is still controversial whether peritumoral edema shown by MRI from preoperative routine scans are associated with patient survival. The aim of this study was to assess the prognostic value of preoperative MRI features in patients with glioblastoma. A retrospective review of 87 patients with newly diagnosed supratentorial glioblastoma was performed using medical records and MRI data from routine scans. The Kaplan-Meier method and COX proportional hazard model were applied to evaluate the prognostic impact on overall survival of pretreatment MRI features (including peritumoral edema, edema shape, necrosis, cyst, enhancement, tumor crosses midline, edema crosses midline, and tumor size). In addition to patient age, Karnofsky performance status (KPS) and postoperative chemoradiotherapy, peritumoral edema extent and necrosis on preoperative MRI were independent prognostic indicator for poor survival. Furthermore, patients with two unfavorable conditions (major edema and necrosis) had a shorter overall survival compared with the remainder. Our data confirm that peritumoral edema extent and necrosis are helpful for predicting poor clinical outcome in glioblastoma. These features were easy to determine from routine MRI scans postoperatively and therefore could provide a certain instructive significance for clinical activities.
Publisher: England: BioMed Central Ltd
Language: English
Identifier: ISSN: 1477-7819
EISSN: 1477-7819
DOI: 10.1186/s12957-015-0496-7
PMID: 25886608
Source: GFMER Free Medical Journals
MEDLINE
PubMed Central
Springer Nature OA/Free Journals
ROAD: Directory of Open Access Scholarly Resources
ProQuest Central
DOAJ Directory of Open Access Journals

Back to results list

Previous Result 15 Next Go to Next page


INSPIRE LIBRARY - TON DUC THANG UNIVERSITY	(84-028) 37 755 057	Feedback
19 Nguyen Huu Tho St. Dist.7, HCM	thuvien@tdtu.edu.vn	Feedback

Peritumoral edema shown by MRI predicts poor clinical outcome in glioblastoma

COPYRIGHT 2015 BioMed Central Ltd. ;COPYRIGHT 2015 BioMed Central Ltd. ;Wu et al.; licensee BioMed Central. 2015 ;ISSN: 1477-7819 ;EISSN: 1477-7819 ;DOI: 10.1186/s12957-015-0496-7 ;PMID: 25886608

Searching Remote Databases, Please Wait