skip to main content
Language:
Search Limited to: Search Limited to: Resource type Show Results with: Show Results with: Search type Index

Comparative study of fine needle aspiration cytology and histopathology in thyroid nodules at a tertiary care hospital: First report from Somalia

Asian journal of surgery, 2023-10, Vol.46 (10), p.4202-4207 [Peer Reviewed Journal]

2022 Asian Surgical Association and Taiwan Robotic Surgery Association ;ISSN: 1015-9584 ;DOI: 10.1016/j.asjsur.2022.11.097

Full text available

Citations Cited by
  • Title:
    Comparative study of fine needle aspiration cytology and histopathology in thyroid nodules at a tertiary care hospital: First report from Somalia
  • Author: Abdullahi, Ismail Mohamud ; Yasin, Nor Abdi ; Dirken, Esin Seren ; Mohamoud, Abdillahi Mohamed ; Guler, Ilkay ; Adani, Abdulkamil Abdullahi
  • Subjects: Diagnostic accuracy ; Fine needle aspiration cytology (FNAC) ; Thyroid cancer
  • Is Part Of: Asian journal of surgery, 2023-10, Vol.46 (10), p.4202-4207
  • Description: FNAC is a minimally invasive procedure and cost-effective, especially in developing countries where patients are mostly poor and surgery is not affordable. The present is the first study that examines the correlation between FNAC and histopathology in diagnosing thyroid cancers at a tertiary hospital in Somalia. This study included 231 patients with thyroid lesions who underwent pre-operative FNACs and histopathologic examination over five years. Investigated clinical parameters include sociodemographic and clinical features and cyto-histopathological findings. The mean patient age was 39.3 ± 15.5 years, and there was a significant female predominance (n = 194; 84%), with a female to male ratio of 5.2:1. The overall sensitivity, specificity, and accuracy rate of cyto-histopathology correlation was 91.1%, 96.6%, and 94.9%, respectively. According to the Bethesda classification system of thyroid FNACs, (n = 141, 61%) of cases were Bethesda II (Benign), of which 95.7% of patients had a benign final histological diagnosis, while 4.3% had malignancy (6 false-negative results). Twenty-two patients (9.5%) were Bethesda III, (n = 3,1.3%) were Bethesda IV (suspicious for neoplasm), and all cases had a follicular adenoma on their final histological diagnosis. Forty-four of the patients were Bethesda V, found in 88.6% of its final histological diagnosis, while 11.4% were benign. Bethesda IV accounted for 9.1%, and all patients in this group were papillary thyroid carcinoma on its final histological confirmation. Our study findings revealed that FNAC of thyroid lesions has a high accuracy rate, sensitivity, and specificity, allowing appropriate initial diagnostic management. It should be applied as the first investigative tool for thyroid lesions.
  • Publisher: Elsevier B.V
  • Language: English
  • Identifier: ISSN: 1015-9584
    DOI: 10.1016/j.asjsur.2022.11.097
  • Source: Geneva Foundation Free Medical Journals at publisher websites
    DOAJ Directory of Open Access Journals

Searching Remote Databases, Please Wait