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The Challenge of Re-treatment Pulmonary Tuberculosis at Two Teaching and Referral Hospitals in Uganda

African health sciences, 2007-09, Vol.7 (3), p.136-142 [Peer Reviewed Journal]

Copyright 2007 - Makerere Medical School, Uganda ;Copyright © Makerere Medical School, Uganda 2007 2007 ;ISSN: 1680-6905 ;EISSN: 1729-0503 ;PMID: 18052866

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  • Title:
    The Challenge of Re-treatment Pulmonary Tuberculosis at Two Teaching and Referral Hospitals in Uganda
  • Author: Anyama, Norbert ; Sseguya, Simon ; Okwera, Alphonse ; El-Naggar, Wael A ; Mpagi, Fred ; Owino, Erisa
  • Subjects: Adolescent ; Adult ; Cross-Sectional Studies ; Female ; Hospitals, Teaching ; Humans ; Interviews as Topic ; Male ; Medical Audit ; Middle Aged ; Original ; prevalence ; pulmonary ; re-treatment ; Retreatment ; Tuberculosis ; Tuberculosis, Pulmonary - diagnosis ; Tuberculosis, Pulmonary - drug therapy ; Tuberculosis, Pulmonary - epidemiology ; Uganda - epidemiology
  • Is Part Of: African health sciences, 2007-09, Vol.7 (3), p.136-142
  • Description: With an annual tuberculosis (TB) incidence of about 350 cases per 100,000 of the population, Uganda is a high burden country. Moreover, it is evident that some TB patients have been treated for a previous episode of the disease. To highlight the burden of re-treatment pulmonary TB and examine patient factors associated with re-treatment among adults at two teaching and referral hospitals, Mbarara and Mulago. A descriptive cross sectional study with data collection between September 2004 and March 2005; we calculated the prevalence and used logistic regression to explore factors associated with re-treatment. The prevalence of re-treatment pulmonary TB at Mbarara based on medical records was 30.0% (95%CI: 21.2 to 40.0), and 21.3% (95%CI: 12.9 to 31.8) from exit interviews. The corresponding estimates at Mulago hospital were 12.0% (95% CI: 6.4 to 20.0) and 43.9% (33.0 to 55.3). Compared to the 18-26 year age category, the prevalence odds ratio (POR) for a seven-year increase in age was 1.54 (95%CI: 1.04-2.28; p = 0.027), while female patients were 0.39 (95%CI: 0.17-0.90; p = 0.025) times less likely to report re-treatment disease than males, in this facility-based study. Re-treatment pulmonary TB is frequent at the two teaching and referral hospitals. A contribution to re-treatment prevention should entail more rigorous management of new TB cases, particularly at lower levels of care.
  • Publisher: Uganda: Makerere University Medical School
  • Language: English
  • Identifier: ISSN: 1680-6905
    EISSN: 1729-0503
    PMID: 18052866
  • Source: African Journals Online (Open Access)
    GFMER Free Medical Journals
    MEDLINE
    PubMed Central
    Bioline International

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